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Liquid Chromatography-Mass Spectrometry

Liquid Chromatography-Mass Spectrometry

A constructive evaluation of the most significant developments in liquid chromatography–mass spectrometry (LC–MS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines Liquid Chromatography–Mass Spectrometry Third Edition offers a well-rounded coverage of the latest technological developments and applications. As the technology itself has matured into a reliable analytical method over the last 15 years the most exciting developments occur in LC–MS augments research into new applications. This edition places a stronger emphasis than previous editions on the impact of LC–MS methods dedicating two-thirds of the text to small-molecule and biomolecular applications such as proteomics pharmaceutical drug discovery and development biochemistry clinical analysis environmental studies and natural products research. Supported by the most relevant literature available each chapter examines how the strategies technologies and recent advances—from sample pretreatment to data processing—in LC–MS helped to shape these disciplines. Featuring new chapters and extensive revisions throughout the book Liquid Chromatography–Mass Spectrometry Third Edition continues to provide scientists with a definitive guide and reference to the most important principles strategies and experimental precedents for applying LC–MS to their research. | Liquid Chromatography-Mass Spectrometry

GBP 44.99
1

Hyphenated and Alternative Methods of Detection in Chromatography

Hyphenated and Alternative Methods of Detection in Chromatography

Widely employed for separating and detecting chemicals in solution separation techniques are most often applied in tandem subsequently referred to as hyphenated methods. Hyphenated and Alternative Methods of Detection in Chromatography details the development and application of mass spectral detection techniques coupled with gas phase and liquid phase chromatographies. With contributions from experts in a variety of fields as evidenced by the range of topics the book describes the advantages and disadvantages of various separation techniques and addresses methods for cutting-edge applications such as proteomics research. Specifically this book covers:The development of the LC-NMR and its application in chromatographic science particularly in relation to the analysis of natural and environmental samples and in the study of reaction monitoring biosynthetic analysis and structural elucidationThe application of LC-ICP in biological samples for the speciation of organoarsenic and organoselenium compounds; metal complexes in microorganisms plants and foods of plant origin; human body fluids and tissues; and in the detection of chemical warfare agentsElectrochemical detection in liquid chromatography system optimization and applications in the analysis of flavonoidsThe use of chemiluminescence for microcolumn and capillary methods of separationThe process of employing multidimensional separation methods as a means of identifying components in complex samplesA detailed reference for those starting out in the field this book also suits those who are more experienced yet require assistance in new directions. It is an ideal reference for senior undergraduate and postgraduate students wishing to supplement their learning experience. Containing over 800 references this book is an excellent source of information within the field of

GBP 59.99
1

Electronic Circuit Analysis using LTSpice XVII Simulator A Practical Guide for Beginners

Electronic Circuit Analysis using LTSpice XVII Simulator A Practical Guide for Beginners

This text discusses simulation process for circuits including clamper voltage and current divider transformer modeling transistor as an amplifier transistor as a switch MOSFET modeling RC and LC filters step and impulse response to RL and RC circuits amplitude modulator in a step-by-step manner for more clarity and understanding to the readers. It covers electronic circuits like rectifiers RC filters transistor as an amplifier operational amplifiers pulse response to a series RC circuit time domain simulation with a triangular input signal and modulation in detail. The text presents issues that occur in practical implementation of various electronic circuits and assist the readers in finding solutions to those issues using the software. Aimed at undergraduate graduate students and academic researchers in the areas including electrical and electronics and communications engineering this book: Discusses simulation of analog circuits and their behavior for different parameters. Covers AC/DC circuit modeling using regular and parametric sweep methods. The theory will be augmented with practical electrical circuit examples that will help readers to better understand the topic. Discusses circuits like rectifiers RC filters transistor as an amplifier and operational amplifiers in detail. | Electronic Circuit Analysis using LTSpice XVII Simulator A Practical Guide for Beginners

GBP 82.99
1

Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis

Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis

Due to its high sensitivity and selectivity liquid chromatography–mass spectrometry (LC–MS) is a powerful technique. It is used for various applications often involving the detection and identification of chemicals in a complex mixture. Ultra Performance Liquid Chromatography Mass Spectrometry: Evaluation and Applications in Food Analysis presents a unique collection of up-to-date UPLC-MS/MS methods for the separation and quantitative determination of components contaminants vitamins and aroma and flavor compounds in a wide variety of foods and food products. The book begins with an overview of the history principles and advancement of chromatography. It discusses the use of UHPLC techniques in food metablomics approaches for analysis of foodborne carcinogens and details of UPLC-MS techniques used for the separation and determination of capsaicinoids. Chapters describe the analysis of contaminants in food including pesticides aflatoxin perfluorochemicals and acrylamide as well as potentially carcinogenic heterocyclic amines in cooked foods. The book covers food analysis for beneficial compounds such as the determination of folate vitamin content analysis applications for avocado metabolite studies virgin olive oil component analysis lactose determination in milk and analysis of minor components of cocoa and phenolic compounds in fruits and vegetables. With contributions by experts in interdisciplinary fields this reference offers practical information for readers in research and development production and routing analysis of foods and food products. | Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis

GBP 44.99
1

Liquid Crystal Sensors

Liquid Crystal Sensors

Liquid Crystal Sensors discusses novel applications of liquid crystals that lie beyond electrically driven optical switches and displays. The main focus is on recent progress in the area of sensors based on low molar mass and polymer liquid crystals. This area of research became hot in recent years since the possibilities for applications of liquid crystal sensors are growing in many areas ranging from the detection of mechanical displacements to the detection of environmental pollutants and chemical agents. This book is well-suited for students as well as scientists from different backgrounds. For students and researchers new to the field it gives a thorough introduction. For experienced researchers it shows the latest breakthroughs and serves as an inspiration for solving problems or sparking new ideas. Key Features:Emphasizes how liquid crystals are extremely sensitive to external stimuli and therefore can be used for the construction of stimuli-responsive devices such as sensors Includes the contributions of editors who are deeply involved in the field and author chapters on hot topics such as the sensitivity of liquid crystals to pollutants UV light and strainProvides an exclusive on LC sensors where having the data in one place will be very useful to the community Gives more information on sensors and broadens the scope by having a contributed volume rather than authored Combines recent data on advances in the area of liquid crystal sensors that includes many types of liquid crystal materials

GBP 44.99
1

Handbook of HPLC

Handbook of HPLC

High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the publication of the benchmark first edition twelve years ago. It reports detailed information on fundamental and practical aspects of HPLC related to conventional format and sophisticated novel approaches which have been developed to address a variety of separation problems in different fields. The latest conceptsNew concepts presented in this edition include monolithic columns bonded stationary phases micro-HPLC two-dimensional comprehensive liquid chromatography gradient elution mode and capillary electromigration techniques. The book also discusses LC-MS interfaces nonlinear chromatography displacement chromatography of peptides and proteins field-flow fractionation retention models for ions and polymer HPLC. Fundamentals and applicationsThe first section of the book explores emerging novel aspects of HPLC and related separation methods based on the differential velocity of analytes in a liquid medium under the action of either an electric field (capillary electromigration techniques) or a gravitational field (field-flow fractionation). The section focusing on applications highlights four significant areas in which HPLC is successfully employed: chiral pharmaceutical environmental analysis food analysis and forensic science. Ideal for a widespread audienceExplanatory figures and tables supplement the text and clarify difficult concepts. Extensive references provide gateways to more focused study. Suitable for undergraduates or new practitioners interested in improving their knowledge on the current status and future trends of HPLC the book is also a critical resource for researchers looking for solutions to complex separation problems or those who currently use HPLC either as an analytical or a preparative scale tool.

GBP 44.99
1