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Multi-Dimensional Liquid Chromatography Principles Practice and Applications

Multi-Dimensional Liquid Chromatography Principles Practice and Applications

Two-dimensional liquid chromatography (2D-LC) is finding increasingly wide application principally due to the analysis of mixtures of moderate to high complexity. Many industries are developing increasingly complex products that are challenging the separation capabilities of state-of-the-art 1D-LC and need new analytical methodologies with substantially more resolving power and 2D-LC meets that need. This text organized by two leaders in the field establishes a sound fundamental basis for the principles of the technique followed by a discussion of important practical considerations. The book begins with an introduction to multi-dimensional separations and a discussion of the history and development of the technique over the past 40 years followed by several chapters that provide a theoretical basis for development of 2D-LC methods including foundational concepts regarding separation complementarity under-sampling and dynamics of liquid chromatography separations. Instrumentation for 2D-LC is discussed extensively including practical aspects such as interface selection and setup. Building on this foundation two separate chapters are focused on method development for non-comprehensive and comprehensive separations followed by a chapter dedicated to data analysis. Finally applications of 2D-LC in several fields ranging from pharmaceutical analysis to polymer science are summarized. The book is an important resource for both students and practitioners who are already using 2D-LC or are interested in getting started in the field. Key Features: Demonstrates the conditions under which a 2D-LC method should be considered as an alternative to a 1D-LC method Establishes a sound fundamental basis of the principles of the technique followed by guidelines for method optimization Provides a single source for technical knowledge advances and practical guidance described in recent literature Assists with the initial decision to develop a 2D-LC method Guides the reader in developing a high-quality method that meets the needs of their application | Multi-Dimensional Liquid Chromatography Principles Practice and Applications

GBP 180.00
1

Liquid Chromatography-Mass Spectrometry

How To Do Primary Care Research

Graphic Design Learn It Do It

Graphic Design Learn It Do It

Graphic Design: Learn It Do It is an introduction to the fundamentals of graphic design and the Adobe Creative Cloud applications used to put these concepts into practice. This book is intended for production-oriented audiences those interested in the what why and how of graphic design. The what is effective graphic design a visual solution created using the design principles that stands out in a crowded marketplace. This discussion includes color theory typography and page layout. Focus on the why of design begins with the reasons why we communicate. Attention is paid to the purpose of the visual solution and to its audiences. The conversation highlights output options (print vs. onscreen) and their related file properties. The how of design addresses the stages of production and use of Adobe Photoshop CC Illustrator CC and InDesign CC to translate an idea into a visual solution. Following an overview of each application and its uses step-by-step exercises are provided to foster familiarity with each application’s workspace and its tools. These exercises provide opportunities to implement the design principles and to produce examples of work for a design portfolio. Key Features: Content based on over a decade’s worth of experience teaching graphic design Contemporary examples and online references Guided exercises for working in the Adobe Creative Cloud applications Photoshop CC Illustrator CC and InDesign CC Accompanying exercise files and supporting materials available for download from the book’s companion website Discussion questions and activities included at the end of chapters to expand the presented topics | Graphic Design Learn It Do It

GBP 49.99
1

The Shortcut Why Intelligent Machines Do Not Think Like Us

The Shortcut Why Intelligent Machines Do Not Think Like Us

An influential scientist in the field of artificial intelligence (AI) explains its fundamental concepts and how it is changing culture and society. A particular form of AI is now embedded in our tech our infrastructure and our lives. How did it get there? Where and why should we be concerned? And what should we do now? The Shortcut: Why Intelligent Machines Do Not Think Like Us provides an accessible yet probing exposure of AI in its prevalent form today proposing a new narrative to connect and make sense of events that have happened in the recent tumultuous past and enabling us to think soberly about the road ahead. This book is divided into ten carefully crafted and easily digestible chapters. Each chapter grapples with an important question for AI. Ranging from the scientific concepts that underpin the technology to wider implications for society it develops a unified description using tools from different disciplines and avoiding unnecessary abstractions or words that end with -ism. The book uses real examples wherever possible introducing the reader to the people who have created some of these technologies and to ideas shaping modern society that originate from the technical side of AI. It contains important practical advice about how we should approach AI in the future without promoting exaggerated hypes or fears. Entertaining and disturbing but always thoughtful The Shortcut confronts the hidden logic of AI while preserving a space for human dignity. It is essential reading for anyone with an interest in AI the history of technology and the history of ideas. General readers will come away much more informed about how AI really works today and what we should do next. | The Shortcut Why Intelligent Machines Do Not Think Like Us

GBP 22.99
1

The High Cost of Low Morale...and what to do about it

EMI Filter Design

EMI Filter Design

With today’s electrical and electronics systems requiring increased levels of performance and reliability the design of robust EMI filters plays a critical role in EMC compliance. Using a mix of practical methods and theoretical analysis EMI Filter Design Third Edition presents both a hands-on and academic approach to the design of EMI filters and the selection of components values. The design approaches covered include matrix methods using table data and the use of Fourier analysis Laplace transforms and transfer function realization of LC structures. This edition has been fully revised and updated with additional topics and more streamlined content. New to the Third Edition Analysis techniques necessary for passive filter realization Matrix method and transfer function analysis approaches for LC filter structure design A more hands-on look at EMI filters and the overall design process Through this bestselling book’s proven design methodology and practical application of formal techniques readers learn how to develop simple filter solutions. The authors examine the causes of common- and differential-mode noise and methods of elimination the source and load impedances for various types of input power interfaces and the load impedance aspect of EMI filter design. After covering EMI filter structures topologies and components they provide insight into the sizing of components and protection from voltage transients discuss issues that compromise filter performance and present a goal for a filter design objective. The text also includes a matrix method for filter design explains the transfer function method of LC structures and their equivalent polynomials and gives a circuit design example and analysis techniques. The final chapter presents packaging solutions of EMI filters.

GBP 94.99
1

Liquid Crystals with Nano/Micro Particles and Their Applications

Hyphenated and Alternative Methods of Detection in Chromatography

Hyphenated and Alternative Methods of Detection in Chromatography

Widely employed for separating and detecting chemicals in solution separation techniques are most often applied in tandem subsequently referred to as hyphenated methods. Hyphenated and Alternative Methods of Detection in Chromatography details the development and application of mass spectral detection techniques coupled with gas phase and liquid phase chromatographies. With contributions from experts in a variety of fields as evidenced by the range of topics the book describes the advantages and disadvantages of various separation techniques and addresses methods for cutting-edge applications such as proteomics research. Specifically this book covers:The development of the LC-NMR and its application in chromatographic science particularly in relation to the analysis of natural and environmental samples and in the study of reaction monitoring biosynthetic analysis and structural elucidationThe application of LC-ICP in biological samples for the speciation of organoarsenic and organoselenium compounds; metal complexes in microorganisms plants and foods of plant origin; human body fluids and tissues; and in the detection of chemical warfare agentsElectrochemical detection in liquid chromatography system optimization and applications in the analysis of flavonoidsThe use of chemiluminescence for microcolumn and capillary methods of separationThe process of employing multidimensional separation methods as a means of identifying components in complex samplesA detailed reference for those starting out in the field this book also suits those who are more experienced yet require assistance in new directions. It is an ideal reference for senior undergraduate and postgraduate students wishing to supplement their learning experience. Containing over 800 references this book is an excellent source of information within the field of

GBP 59.99
1

ISO 9001 2015 - A Complete Guide to Quality Management Systems

A First Course in Logic

Naturally Occurring Benzodiazepines Endozepines and their Receptors Implications for Benzodiazepine Therapy and Withdrawal

Naturally Occurring Benzodiazepines Endozepines and their Receptors Implications for Benzodiazepine Therapy and Withdrawal

Understanding and addressing the current opioid crisis requires knowledge of endogenous opioids (endorphins and enkephalins) but there is now evidence for a benzodiazepine crisis. Are there endogenous benzodiazepine-like substances—and what do they do? How do they affect antianxiety drugs and their adverse effects? Do they explain enigmatic prolonged benzodiazepine withdrawal syndrome? This book raises important questions about the clinical consequences of ignoring the existence of or understanding the potential influence of endogenous benzodiazepines on the therapeutic effect of benzodiazepines their adverse effects and the problems of withdrawal from them and other benzodiazepine receptor agonists. FEATURES Discusses endogenous benzodiazepine-like substances—what do they do and do they affect antianxiety drugs and their adverse effects? Presents information on enigmatic prolonged benzodiazepine withdrawal syndrome Describes the compounds acting at the BDZ binding sites both exogenous (classical BDZ drugs and BDZ from food and plants) and endogenous (endozepines) Assesses the putative interactions in physiology pathology and pharmacology of the compounds acting at the BDZ binding sites Dr. Raffa is Adjunct Professor at the University of Arizona College of Pharmacy and Professor Emeritus at Temple University School of Pharmacy. He has co-authored or edited several books on pharmacology and thermodynamics is a co-editor of two journals is a past president of the Mid-Atlantic Pharmacology Society and is the recipient of research and teaching awards. Dr. Amantea is Associate Professor of Pharmacology at the Department of Pharmacy Health and Nutritional Sciences of the University of Calabria (Italy) where she is the leader of the Stroke Research Unit at the Section of Preclinical and Translational Pharmacology operating in the frame of the Italian Stroke Organization (ISO) Basic Science. She is a member of the Editorial Board and the Guest Editor of the 2016 Neuroscience section of Current Opinion in Pharmacology (Elsevier) and the founder and the editor of the CRC Press Frontiers in Neurotherapeutics series. | Naturally Occurring Benzodiazepines Endozepines and their Receptors Implications for Benzodiazepine Therapy and Withdrawal

GBP 64.99
1

Cybersecurity for Everyone

Handbook of Pharmaceutical Manufacturing Formulations Volume Three Liquid Products

Electronic Circuit Analysis using LTSpice XVII Simulator A Practical Guide for Beginners

Consulting in a Nutshell A practical guide to successful general practice consultations before during and beyond the MRCGP

Consulting in a Nutshell A practical guide to successful general practice consultations before during and beyond the MRCGP

‘…a unique book written by a unique GP. There is no-one better placed to pull together decades of learning and experience on how to achieve the greatest success in the general practice consultation. The relaxed pace of writing the accessible examples the clear narrative and the engaging anecdotes make this a resource that it is accessible and useful to all who seek to improve their clinical consulting skills. ’ Helen Stokes-Lampard former Chair of the Royal College of General Practitioners This brand-new book aims to help GPs establish ways of thinking talking and behaving in the consultation that are most likely to lead to good outcomes. It describes a simple three-part approach to the consultation’s essential task which is to convert a patient’s problem into a plan acceptable to both patient and doctor. It combines reader-friendly explanations helpful illustrations and examples from everyday practice. Key features: Written by a respected GP teacher and author of the highly-regarded trilogy The Inner Consultation The Inner Apprentice and The Inner Physician Gives GPs a framework for consulting that is easy to remember comprehensive adaptable robust exam-friendly and quickly becomes second nature Identifies and addresses key areas of anxiety for GP trainees and MRCGP candidates including ‘How do I complete in 10 minutes?’ ‘How do I deal with difficult patients?’ and ‘What do I do when it all goes pear-shaped and I don’t know what to do?’ Gives advice and practical suggestions for how to make the difficult transition from theory to practice from reading about the consultation to actually doing it better in real life Consulting in a Nutshell will help GPs at every career stage – from medical student to CSA candidate to experienced practitioner – to analyse develop and grow their personal consulting style. Coming at a time of profound change in primary care it aims to ensure that seeing patients and having good consultations becomes and remains a source of satisfaction and fulfilment. The author:Roger Neighbour is a retired GP former Convenor of the Panel of MRCGP Examiners and past President Royal College of General Practitioners UK. | Consulting in a Nutshell A practical guide to successful general practice consultations before during and beyond the MRCGP

GBP 26.99
1

Handbook of Industrial Engineering Equations Formulas and Calculations

Handbook of Industrial Engineering Equations Formulas and Calculations

The first handbook to focus exclusively on industrial engineering calculations with a correlation to applications Handbook of Industrial Engineering Equations Formulas and Calculations contains a general collection of the mathematical equations often used in the practice of industrial engineering. Many books cover individual areas of engineering and some cover all areas but none covers industrial engineering specifically nor do they highlight topics such as project management materials and systems engineering from an integrated viewpoint. Written by acclaimed researchers and authors this concise reference marries theory and practice making it a versatile and flexible resource. Succinctly formatted for functionality the book presents:Basic Math CalculationsEngineering Math CalculationsProduction Engineering CalculationsEngineering Economics CalculationsErgonomics CalculationsFacility Layout CalculationsProduction Sequencing and Scheduling CalculationsSystems Engineering CalculationsData Engineering CalculationsProject Engineering CalculationsSimulation and Statistical EquationsIt has been said that engineers make things while industrial engineers make things better. To make something better requires an understanding of its basic characteristics and the underlying equations and calculations that facilitate that understanding. To do this however you don’t have to be computational experts; you just have to know where to get the computational resources that are needed. This book elucidates the underlying equations that facilitate the understanding required to improve design processes continuously improving the answer to the age-old question: What is the best way to do a job?

GBP 66.99
1

Physiology of Marine Mammals Adaptations to the Ocean

Physiology of Marine Mammals Adaptations to the Ocean

Suppose you were designing a marine mammal. What would they need to live in the ocean? How would you keep them warm? What design features would allow them to dive for very long periods to extreme depths? Do they need water to drink? How would they minimize the cost of swimming and how would they find their prey in the deep and dark? These questions and more are examined in detail throughout Marine Mammal Physiology which explores how marine mammals live in the sea from a physiological point of view. This undergraduate textbook considers the essential aspects of what makes a marine mammal different from terrestrial mammals beyond just their environment. It focuses on the physiological and biochemical traits that have allowed this group of mammals to effectively exploit the marine environment that is so hostile to humans. The content of this book is organised around common student questions taking the undergraduate's point of view as the starting point. Each chapter provides a set of PowerPoint slides for instructors to use in teaching and students to use as study guides. New Study Questions and Critical Thinking Points conclude each chapter which are each motivated by a Driving Question such as How do mammals stay warm in a cold ocean? or How do mammals survive the crushing pressures of the deep sea? Full-colour images and comprehensive accessible content make this the definitive textbook for marine mammal physiology. | Physiology of Marine Mammals Adaptations to the Ocean

GBP 49.99
1

Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis

Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis

Due to its high sensitivity and selectivity liquid chromatography–mass spectrometry (LC–MS) is a powerful technique. It is used for various applications often involving the detection and identification of chemicals in a complex mixture. Ultra Performance Liquid Chromatography Mass Spectrometry: Evaluation and Applications in Food Analysis presents a unique collection of up-to-date UPLC-MS/MS methods for the separation and quantitative determination of components contaminants vitamins and aroma and flavor compounds in a wide variety of foods and food products. The book begins with an overview of the history principles and advancement of chromatography. It discusses the use of UHPLC techniques in food metablomics approaches for analysis of foodborne carcinogens and details of UPLC-MS techniques used for the separation and determination of capsaicinoids. Chapters describe the analysis of contaminants in food including pesticides aflatoxin perfluorochemicals and acrylamide as well as potentially carcinogenic heterocyclic amines in cooked foods. The book covers food analysis for beneficial compounds such as the determination of folate vitamin content analysis applications for avocado metabolite studies virgin olive oil component analysis lactose determination in milk and analysis of minor components of cocoa and phenolic compounds in fruits and vegetables. With contributions by experts in interdisciplinary fields this reference offers practical information for readers in research and development production and routing analysis of foods and food products. | Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis

GBP 44.99
1

Liquid Crystal Sensors

Liquid Crystal Sensors

Liquid Crystal Sensors discusses novel applications of liquid crystals that lie beyond electrically driven optical switches and displays. The main focus is on recent progress in the area of sensors based on low molar mass and polymer liquid crystals. This area of research became hot in recent years since the possibilities for applications of liquid crystal sensors are growing in many areas ranging from the detection of mechanical displacements to the detection of environmental pollutants and chemical agents. This book is well-suited for students as well as scientists from different backgrounds. For students and researchers new to the field it gives a thorough introduction. For experienced researchers it shows the latest breakthroughs and serves as an inspiration for solving problems or sparking new ideas. Key Features:Emphasizes how liquid crystals are extremely sensitive to external stimuli and therefore can be used for the construction of stimuli-responsive devices such as sensors Includes the contributions of editors who are deeply involved in the field and author chapters on hot topics such as the sensitivity of liquid crystals to pollutants UV light and strainProvides an exclusive on LC sensors where having the data in one place will be very useful to the community Gives more information on sensors and broadens the scope by having a contributed volume rather than authored Combines recent data on advances in the area of liquid crystal sensors that includes many types of liquid crystal materials

GBP 44.99
1

Effective Ecology Seeking Success in a Hard Science

Effective Ecology Seeking Success in a Hard Science

Ecology is one of the most challenging of sciences with unambiguous knowledge much harder to achieve than it might seem. But it is also one of the most important sciences for the future health of our planet. It is vital that our efforts are as effective as possible at achieving our desired outcomes. This book is intended to help individual ecologists to develop a better vision for their ecology – and the way they can best contribute to science. The central premise is that to advance ecology effectively as a discipline ecologists need to be able to establish conclusive answers to key questions rather than merely proposing plausible explanations for mundane observations. Ecologists need clear and honest understanding of how we have come to do things the way we do them now the limitations of our approaches our goals for the future and how we may need to change our approaches if we are to maintain or enhance our relevance and credibility. Readers are taken through examples to show what a critical appraisal can reveal and how this approach can benefit ecology if it is applied more routinely. Ecological systems are notable for their complexity and their variability. Ecology is as indicated by the title of this book a truly difficult science. Ecologists have achieved a great deal but they can do better. This book aims to encourage early-career researchers to be realistic about their expectations: to question everything not to take everything for granted and to make up their own minds. | Effective Ecology Seeking Success in a Hard Science

GBP 54.99
1

Workflow A Practical Guide to the Creative Process