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Interleukin-2 and Killer Cells in Cancer

Interleukin-2 and Killer Cells in Cancer

This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer the basic and clinical investigations in the IL-2 field are rapidly expanding together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists clinicians and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible. | Interleukin-2 and Killer Cells in Cancer

GBP 145.00
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Automotive Technician Training: Practical Worksheets Level 2

Automotive Technician Training: Practical Worksheets Level 2

Automotive practical worksheets and assessments for students at Level 2 This Level 2 Student Worksheets book contains tasks that help you develop practical skills and prepare you for assessment. The tasks also reinforce the automotive theory that you will learn online and in the classroom. Each worksheet covers individual topics in a step-by-step manner detailing how to carry out all of the most important tasks contained within the syllabus. Alongside each of these worksheets is a job card that can be filled in and used as evidence towards your qualification. Endorsed by the Institute of the Motor Industry for all of their Level 2 automotive courses. Step-by-step guides to the practical tasks required at all Level 2 qualifications. Job sheets for students to complete and feedback sheets for assessors to complete. | Automotive Technician Training: Practical Worksheets Level 2

GBP 175.00
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Lollipop Logic Critical Thinking Activities (Book 2 Grades K-2)

Lollipop Logic Critical Thinking Activities (Book 2 Grades K-2)

Lollipop Logic employs visual and pictorial clues to introduce and reinforce high-powered thinking for pre-readers. Seven different thinking skills—sequences relationships analogies deduction pattern decoding inference and critical analysis—are presented in a format designed to appeal to gifted young learners. This straightforward one-of-a-kind tool gives wings to pre-readers and non-readers who are ready for a challenge but don’t yet have the reading skills for more traditional critical thinking activities. Now with full-color illustrations this beloved classic has been fully updated with refreshed activities images and text to help young learners continue to soar into the stratosphere of thinking skills far beyond their reading levels. | Lollipop Logic Critical Thinking Activities (Book 2 Grades K-2)

GBP 120.00
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Weed Physiology Volume 2: Herbicide Physiology

Weed Physiology Volume 2: Herbicide Physiology

Volume 2 deals with the mechanisms of herbicide action and of resistance and tolerance to herbicides. The first five chapters of this volume cover the effects of herbicides and adjuvants on the physiology of plants. Professor Black‘s chapter begins by covering the effects of herbicides on photosynthesis including photosynthetic assimilation of nitrogen sulfur and phosphorus. This is followed by Dr. Morelands chapter on herbicide interactions with plant respiration. The third chapter by Professor Bartels deals with the effects of herbicides on chloroplast and cellular development with emphasis on correlating physiological information with ultrasound effects. | Weed Physiology Volume 2: Herbicide Physiology

GBP 170.00
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Handbook of Obesity - Volume 2 Clinical Applications

Handbook of Obesity - Volume 2 Clinical Applications

Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation diagnosis prevention and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition including the effect of SARS-CoV-2 on people with obesity the concept of “Precision Medicine” and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%. This volume is structured into 5 parts: Part 1 provides insights from evolution on changes in diet and physical activity and the implications and results for preventing obesity health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment Part 2 deals with evaluation of overweight patients approaches for classifying obesity and using this knowledge to evaluate patients and addressing ethnic and racial considerations in evaluating patients with obesity Part 3 explains the impact of lifestyle in managing obesity which include behavioural management diet dietary composition and meal timing and the effects of physical activity and exercise in weight loss and weight loss maintenance Part 4 is focused on medications in the management of obesity. This includes drug selection various classes of drugs combination of drugs affecting weight loss effect of herbal agents on weight loss and treatment of obesity in pediatric populations genetic diseases causing obesity and the role of drugs in treating the dyslipidemias Part 5 discusses bariatric surgery its history procedure and effects in details and other surgical techniques including electric stimulation of the vagus nerve gastric balloons intestinal liners and liposuction | Handbook of Obesity - Volume 2 Clinical Applications

GBP 150.00
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Instant DVD Workshop 2

Instant DVD Workshop 2

Ulead DVD Workshop is DVD-authoring software designed for video professionals and enthusiasts working on the Windows platform. It permits users to import video from digital or analog sources with sophisticated MPEG capture and conversion tools and build professional looking still or motion menus using an extensive set of design tools. Instant DVD Workshop 2. 0 presents carefully detailed screen shots and step-by-step directions illustrating how to use DVD Workshop software. Beginning with the proper installation of the application it covers the full scope of functions including managing media importing stills and graphics editing video inserting audio files creating menus and finish authoring with professional tips and techniques covering workflow and other topics provided along the way.

GBP 175.00
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Get Through MRCOG Part 2: MCQs

Get Through MRCOG Part 2: MCQs

Get Through MRCOG Part 2: MCQs covers the breadth and depth of the MRCOG Part 2 examination syllabus and is an essential revision tool for candidates preparing for this examination. The comprehensive and wide collection of practice questions is designed to help the candidate test and assess their knowledge of the subject aiding them in thorough preparation for the exam. The text contains 750 multiple choice stems each with around four associated questions providing the reader with a total of 3000 individual questions with which to test themselves. The material is divided up by subject area allowing candidates to test their knowledge on a particular topic. The 13 'modules' are followed by two mock papers each containing a selection of questions on different subject areas which the reader can attempt under timed conditions. Answers are provided with useful explanatory information for all questions to help the reader understand why their answer is right or wrong. The author Paul Ayuk was clinical lecturer in obstetrics and gynaecology at Oxford University for 6 years and has run an on-line MRCOG course for over 5 years assisting over 8000 candidates worldwide.

GBP 130.00
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English Homework for Key Stage 2 Activity-Based Learning

English Homework for Key Stage 2 Activity-Based Learning

English Homework for Key Stage 2 is a unique resource for busy teachers - a selection of ‘pencil-free’ hands-on activities aligned with the National Curriculum Programmes of Study and with clear links to the topics set out in the PNS Framework for English that teachers can use as extension activities or give to pupils as homework to do with members of their family or friends. Each of the activities encourages the pupils to learn through discussion and through practical activities utilising everyday resources. Each activity is quick and easy for pupils and teachers to manage and includes: a learning aim full clear instructions and discussion points tasks to foster collaboration and partnership between pupils parents and teachers photocopiable resources. A refreshing approach for teachers and pupils these activities will foster enthusiasm for learning and inspire pupils' interest in English. | English Homework for Key Stage 2 Activity-Based Learning

GBP 130.00
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Current Topics in Nonclinical Drug Development Volume 2

Current Topics in Nonclinical Drug Development Volume 2

The second volume in the CURRENT TOPICS IN NONCLINICAL DRUG DEVELOPMENT SERIES explores the critical issues and current topics in nonclinical drug development. This second volume covers individual topics and strategies in drug development from compound characterization to drug registration. Written by a variety of experts in the field recent and rapid advances in technologies and associated changes in regulatory guidance are discussed. Select topics include: Evolution of Artificial Intelligence (AI) technologies and the impact on toxicologic pathology. Current approaches to carcinogenicity testing. Predicting drug-drug interactions. Current understanding of idiosyncratic drug reaction. Assessing cardiovascular risks beyond QT interval. Use of 3D cell cultures in toxicology and ADME. Development of small molecule-antibody complexes. Differentiating adverse from non-adverse findings in nonclinical studies. Current Topics in Nonclinical Drug Development: Volume 2 will aid toxicologists toxicologic pathologists consultants regulators study directors and nonclinical scientists dealing with day-to-day issues encountered in drug development and assist in formulating strategies for resolution of these issues. In addition the book will be a valuable reference for academicians and graduate students pursuing research related to nonclinical drug development. | Current Topics in Nonclinical Drug Development Volume 2

GBP 170.00
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HTML5 Game Development from the Ground Up with Construct 2

HTML5 Game Development from the Ground Up with Construct 2

Written for the new generation of hobbyists and aspiring game developers HTML5 Game Development from the Ground Up with Construct 2 shows you how to use the sophisticated yet user-friendly HTML5-based game engine Construct 2 to develop and release polished two-dimensional games on a multitude of different platforms. The book also covers the foundational knowledge of game analysis and design based on the author‘s research and teaching experiences at DigiPen Institute of Technology James Cook University and other institutions. The author first helps you understand what really matters in games. He guides you in becoming a better game designer from the ground up being able to play any game critically and expressing your ideas in a clear and concise format. The book then presents step-by-step tutorials on designing games. It explains how to build an arcade-style game as well as a platformer integrating some physics elements. It also shows you how to create a more complex puzzle game the author‘s own published game Turky on the Run. Lastly the book discusses different ways to deploy and monetize games across several platforms including Facebook iOS Android and web-based marketplaces. Sample Construct 2 project files for the games designed in the book are available on the author‘s website. Integrating hands-on guidance with theoretical game design concepts this book gives you a solid foundation in game development. It will help you advance in your journey as an indie game developer.

GBP 175.00
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The Routledge Encyclopedia of Taoism 2-Volume Set

The Routledge Encyclopedia of Taoism 2-Volume Set

The Routledge Encyclopedia of Taoism provides comprehensive coverage of Taoist religion thought and history reflecting the current state of Taoist scholarship. It contains hundreds of entries authored by an international body of experts which cover areas such as schools and traditions texts persons and sacred sites. Terms are given in their original characters transliterated and translated. The encyclopedia is thoroughly cross-referenced and indexed and also includes a chronology and bibliography. It is invaluable for students and scholars in the fields of religious studies philosophy and religion and Asian history and culture. | The Routledge Encyclopedia of Taoism 2-Volume Set

GBP 90.00
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Flavonoids and Anti-Aging The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

Flavonoids and Anti-Aging The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover many critical biological functions linked to cell viability metabolism autophagy inflammation immunity and differentiation have been attributed to Nrf2 which regulates over 600 genes. It is well known that oxidative stress which Nrf2 can ameliorate plays a key role in many pathologic processes such as aging obesity diabetes cancer and neurodegenerative diseases. Flavonoids on the other hand through their ability to activate and upregulate Nrf2 can have anti-oxidative anti-inflammatory anti-mutagenic and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals functional foods and pharmaceuticals. The present book Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf2 and flavonoids and their applications in various conditions such as aging osteoporosis cardiovascular diseases and neurodegenerative disease and many other areas. Key Features: Focuses on the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and WELLNESS molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoid-based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2 which is responsible for many different disease conditions due to increased reactive oxidative species in the body caused by some physiological triggers. | Flavonoids and Anti-Aging The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

GBP 150.00
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Rock Dynamics: Progress and Prospect Volume 2 Proceedings of the Fourth International Conference on Rock Dynamics And Applications (RocDyn

Rock Dynamics: Progress and Prospect Volume 2 Proceedings of the Fourth International Conference on Rock Dynamics And Applications (RocDyn

Rock Dynamics: Progress and Prospect contains 153 scientific and technical papers presented at the Fourth International Conference on Rock Dynamics and Applications (RocDyn-4 Xuzhou China 17-19 August 2022). The two-volume set has 7 sections. Volume 1 includes the first four sections with 6 keynotes and 5 young scholar plenary session papers and contributions on analysis and theoretical development and experimental testing and techniques. Volume 2 contains the remaining three sections with 74 papers on numerical modelling and methods seismic and earthquake engineering and rock excavation and engineering. Rock Dynamics: Progress and Prospect will serve as a reference on developments in rock dynamics scientific research and on rock dynamics engineering applications. The previous volumes in this series (RocDyn-1 RocDyn-2 and RocDyn-3) are also available via CRC Press. | Rock Dynamics: Progress and Prospect Volume 2 Proceedings of the Fourth International Conference on Rock Dynamics And Applications (RocDyn

GBP 150.00
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How to Teach Fiction Writing at Key Stage 2

How to Teach Fiction Writing at Key Stage 2

How to Teach Fiction Writing is a practical manual to help teachers of junior classes to focus on the key aspects of developing children's storywriting. The book presents a series of essential writing workshops full of creative ideas and fun activities. It also offers a range of advice including how to set up and run an effective workshop and how to monitor NLS links. Workshops focus on capturing stories characterization creating settings skilful paragraphing writing in a variety of genres from myths and fables to adventures and science fiction and writing style. | How to Teach Fiction Writing at Key Stage 2

GBP 175.00
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Building Stones of Milan and Lombardy Volume 2: Stones of Lombardy

Building Stones of Milan and Lombardy Volume 2: Stones of Lombardy

Milan and Lombardy have played an important role in the Italian country since the Roman period. This importance is reflected also by the diffusion of stone architecture: a persisting trait of Milan architecture was the use of different stones in the same building. Milan lies in the middle of the alluvial plain of the Po far from the stone quarries; some waterways were dug out in order to supply the building stones from the surrounding territories. The study of stone as building material was significant at the end of 19th century but then it was largely neglected by both architects and geologists. So it is significant to suggest a study about the stones employed to build in Milan (Volume 1) in relationship with a petrographic study about the features of the stones quarried in the whole Lombard territory (Volume 2). Volume 2 contains the description of the features of the stones reported in Volume 1. These features include metamorphic and magmatic rocks of the Alpine area; sedimentary rocks and loose materials of the Prealpine area; sedimentary rocks of the Apennine area; and loose sediments of the Padania plain. Some stones coming from other northern Italian regions and used in Lombard architecture are also described. Each stone is described in a card containing commercial and historical names petrographic classification macroscopic features mineralogical composition microscopic features geological setting quarry sites transport to yards morphology of dressed elements and surface handworking use in architecture in the whole Lombard territory and abroad and decay morphologies. A particular investigation is addressed to the stones used during the 20th century; a great part of them were never used before in Milan and in Lombardy. | Building Stones of Milan and Lombardy Volume 2: Stones of Lombardy

GBP 110.00
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Changing Orders in International Economic Law Volume 2 A Japanese Perspective

Changing Orders in International Economic Law Volume 2 A Japanese Perspective

These two groundbreaking volumes look at complex legal issues in the changing global economy from the perspective of Asia and/or Japan. Contributors scrutinize the past present and future and discuss what the global legal order in economic fields could be like by navigating uncertain and turbulent times. The books address six main themes: (1) Polarization and diversification of values progress of regionalism and restructuring of multilateral rules (2) Full-scale arrival of the digital economy and its impact (3) Empowerment of private persons/entities (4) Reconsideration of the concept of “territorial jurisdiction” (5) Law of national security and rule in emergency situations and (6) Values of Sustainable Development Goals (SDGs) in trade and investment liberalization rules. The books also examine various legal problems under the COVID-19 crisis and suggest how the post-COVID-19 global economic order will be from the perspective of Asia and/or Japan. This comprehensive insight will shed light on the intertwined and complex phenomena of world economy and allow readers of business law and international law to have a better understanding of this volatile era. | Changing Orders in International Economic Law Volume 2 A Japanese Perspective

GBP 130.00
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